Kariya don amfani da desmopressin acetate

Yawan wuce haddi yana ƙara haɗarin riƙe ruwa da hyponatremia.Gudanar da hyponatremia ya bambanta daga mutum zuwa mutum.A cikin marasa lafiya tare da hyponatremia marasa alama, ya kamata a dakatar da desmopressin kuma a hana shan ruwa.A cikin marasa lafiya da alamun hyponatremia, yana da kyau a ƙara isotonic ko hypertonic sodium chloride zuwa drip.A lokuta masu tsauri mai tsauri (ƙuƙwalwa da asarar sani), magani tare da furosemide ya kamata a ƙara.

Marasa lafiya tare da al'ada ko ƙishirwa na psychogenic;angina pectoris maras tabbas;metabolism dysregulation rashin wadatar zuciya;nau'in IIB vascular hemophilia.Ya kamata a ba da kulawa ta musamman ga haɗarin riƙe ruwa.Ya kamata a rage yawan shan ruwa zuwa ƙarami kamar yadda zai yiwu kuma ya kamata a duba nauyi akai-akai.Idan an sami karuwa a hankali a cikin nauyin jiki kuma sodium na jini ya ragu ƙasa da 130 mmol/L ko osmolality na plasma ya faɗi ƙasa da 270 mosm/kg, ya kamata a rage yawan shan ruwa kuma a daina desmopressin.Yi amfani da hankali a cikin marasa lafiya waɗanda suka yi ƙanƙara ko tsofaffi;a cikin marasa lafiya da wasu cututtuka da ke buƙatar maganin diuretic don rashin daidaituwa na ruwa da / ko solubility;kuma a cikin marasa lafiya da ke cikin haɗari don ƙara yawan matsa lamba na intracranial.Ya kamata a auna abubuwan coagulation da lokacin zubar jini kafin amfani da wannan magani;Matsalolin plasma na VIII:C da VWF:AG suna ƙaruwa sosai bayan gudanarwa, amma bai yiwu a kafa alaƙa tsakanin matakan plasma na waɗannan abubuwan da lokacin zubar jini kafin da bayan gudanarwa ba.Don haka idan zai yiwu, tasirin desmopressin akan lokacin zubar jini a cikin masu fama da cutar ya kamata a gwada gwaji.

Ya kamata a daidaita ƙayyadaddun lokacin zubar da jini kamar yadda zai yiwu, misali, ta hanyar Simplate II.Tasiri kan Ciki da Lactation Gwaje-gwajen Haihuwa a cikin berayen da zomaye da aka gudanar a fiye da sau ɗari adadin ɗan adam ya nuna cewa desmopressin ba ya cutar da amfrayo.Wani mai bincike ya ba da rahoton wasu abubuwa uku na rashin lafiya a jariran da aka haifa ga mata masu ciki na uremic da suka yi amfani da desmopressin a lokacin daukar ciki, amma wasu rahotanni na fiye da 120 sun nuna cewa jariran da aka haifa ga matan da suka yi amfani da desmopressin a lokacin daukar ciki sun kasance al'ada.

Bugu da ƙari, wani binciken da aka rubuta da kyau ya nuna cewa ba a samu karuwa a cikin rashin haihuwa ba a cikin jarirai 29 da aka haifa ga mata masu ciki waɗanda suka yi amfani da desmopressin a lokacin dukan ciki.Binciken nono daga mata masu shayarwa da aka yi da allurai masu yawa (300ug intranasal) ya nuna cewa adadin desmopressin da aka ba wa jarirai ya yi ƙasa da adadin da ake buƙata don shafar diuresis da hemostasis.

Shirye-shirye: Magungunan ƙwayoyin cuta na iya haɓaka amsawar mai haƙuri ga desmopressin ba tare da tsawaita lokacin aikin ba.Wasu abubuwa da aka sani don sakin hormones na antidiuretic, irin su tricyclic antidepressants, chlorpromazine, da carbamazepine, suna ƙarfafa tasirin antidiuretic.Yana ƙara haɗarin riƙe ruwa.