Farashin kayan aikin API 99% Ganirelix Acetate 123246-29-7 Mai ƙira

Ganirelix acetate shine analog na GnRH tare da sauye-sauye a ragowar 1, 2, 3, 6, 8, da 10. Ba superagonist ba ne amma, maimakon haka, shi ne decapeptide na roba tare da babban aikin antagonist da kuma farkon GnRH antagonist da za a kasuwa.An yarda da shi don dakatar da hawan jini na LH a cikin matan da ke fama da ciwon hawan jini na ovarian;LH surges kullum suna inganta kwai.Manufar wannan magani shine don rage yawan adadin kwanakin magani da ake bukata don kawar da hawan jini na LH, don haka kiyaye ƙwai a cikin ovaries.Tarin hadi na in vitro (IVF) a tarihi an fara shi ta hanyar gudanar da leuprolide acetate don murkushe sakin LH da wuri.Wannan yana hana kwai ta yadda ƙwai ya kasance yana samuwa don dawo da su daga ƙwararrun haihuwa.Don wannan dalili, leuprolide acetate yawanci ana allurar har tsawon kwanaki 26.Nazarin asibiti ya nuna cewa ganirelix acetate na iya rufe LH karuwa a cikin kwanaki 5 kawai na jiyya, cewa kashewar LH ya fi bayyana fiye da na FSH, kuma cewa ɗan gajeren lokacin jiyya yana rage tasirin sakamako mara kyau, kamar walƙiya mai zafi da ciwon kai. .